Considering an experimental treatment?

Several people have asked my advice on this topic. For obvious reasons, patients can be very eager to try an exciting, new medication or other treatment for their illness. I am a big fan of treatment research for brain diseases. However, this eagerness has also been exploited for … well, forever, to sell snake oil […]

An advance in Huntington disease biology

This isn’t from the Black lab, but colleagues here at Wash.U. have used cells from people with Huntington disease (HD) to discover abnormally high levels of a messenger RNA. That mRNA decreases autophagy–a cell’s ability to clean up its insides–and that hastens the death of the cell. The authors went on to show that they […]